News & Publications - TriAgenics, Inc

Published Research

Fully Guided Tooth Bud Ablation in Pigs Results in Complete Tooth Bud Removal and Molar Agenesis

Leigh E. Colby, DDS, MBA and Dave P. Watson, MSME

Published in the Journal of Oral and Maxillofacial Surgery

Conclusions: The results of this study confirm the hypothesis that healing processes following fully guided tooth bud ablation resulted in removal of targeted tooth bud tissues, complete molar agenesis, and trabecular new bone growth at 28-days post treatment.
Ⓒ 2022 American Association of Oral and Maxillofacial Surgeons 2022

Fully Guided Third Molar Tooth Bud Ablation in Pigs

Leigh E. Colby, DDS, MBA

Published in the Journal of Oral and Maxillofacial Surgery

Conclusions: The animal model developed for this study enabled the demonstration of a fully guided Zero3® TBA protocol. The animal model and 3TBA procedure employed in this study appear to be appropriate for use in future long-term animal studies designed to demonstrate the efficacy of Zero 3® TBA for inducing molar agenesis.
Ⓒ 2022 American Association of Oral and Maxillofacial Surgeons

In The News

Surgery-free way to remove 3rd molars may be coming

In the future, surgery may no longer be needed to manage wisdom teeth. A 3D-guided microwave ablation procedure removed third-molar tooth buds in pigs in minutes, according to a study published in the Journal of Oral and Maxillofacial Surgery.
Read the full article

Special Report: Disruptive Technology and Innovation in OMS

Tooth Bud Ablation by Leigh Colby, DDS, MBA, TriAgenics,Inc.
Published in Face to Face® October 2021.
Read the full article

A New Paradigm for Third Molar Management

The Clinical Rational Behind Fully Guided Third Molar Tooth Bud Ablation
Leigh Colby, DDS, MBA
With the evolution of guided implant placement, dentists have an opportunity to reimagine how they manage third molars.
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2024 Must Know Dental Technique

As we look ahead to 2024, it’s always interesting to predict which technologies and techniques will become a regular part of the dental industry in the near future.
Read the full article about the revolutionary Zero3® TBA technology

Dr. Bicuspid’s Kevin Henry interviews Dr. Leigh Colby, DDS, MBA to learn more about TriAgenics® and third molar tooth ablation.

This is an episode of the “Everyday Oral Surgery” podcast in which Dr. Grant Stucki interviews Dr. Leigh Colby, DDS, MBA, President of TriAgenics® to understand the inspiration and the science behind his patented Zero3® TBA (third molar tooth bud ablation) procedure. The Zero3® TBA procedure prevents wisdom teeth from ever forming thereby eliminating all of the complications associated with wisdom teeth extractions. Listen now to learn more about this exciting new technology.

Eliminate Third Molar Complications With 3TBA

TriAgenics®’ fully guided tooth bud ablation treatment (Zero3® TBA) is designed to eliminate problems associated with current third molar management strategies.
Leigh Colby, DDS, MBA
Managing complication associated with third molar removal is an enormous challenge for clinicians, and it’s painful and costly for patients.
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New Technology Designed to Eliminate Third Molar Complications.

A high precision, fully guided micro-ablation system has been developed to eliminate the postoperative problems normally associated with third molar formation.
Leigh Colby, DDS, MBA
Third molar removal is one of the most common surgeries performed in the United States and Europe. Unfortunately, the highly invasive nature of third molar surgery results in a predictable range of painful complications.
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targeted microwave ablation that prevents wisdom teeth from ever forming

Minimally Invasive Guided Ablation Technology as an Alternative to Surgical Extraction

This clinical case report, published by the Ontario Dental Association, describes TriAgenics’ innovative approach to third molar management. The article appears in the June 2025 edition of Ontario Dentist.
Kelsey O’Hagan-Wong
DDS MSc (Pediatric Dentistry)
Theodore Ratelle
BID MD (Master of Dentistry)
Read the Clinical Case Report