Zero3™ Animal Trials
TriAgenics has conducted extensive animal testing (live animal and ex vivo bench-level tissue testing) to demonstrate the safety and efficacy of its Zero3 TBA (3rd molar Tooth Bud Ablation) technology. Phase I live animal testing in 2015 demonstrated the ability to consistently perform the 3TBA procedure. TriAgenics Zero3 technology has been engineered to control all aspects of the Zero3 TBA process to make the procedure safe, effective and simple. As demonstrated in multiple animal studies, Zero3 TBA predictably blocks molar agenesis. Additional live animal studies are planned to optimize the thermal ablation process to minimize damage outside the tooth bud. The menu items below provide a representative overview of TriAgenics’ animal testing program. Our animal testing program will result in a request IDE application submission to the FDA in 2019.